Support the Multiple Sclerosis Registry

The registry aims to provide clinicians with meaningful insights into treatment response, support evidence‑based use of high‑cost therapies, and create a long‑term resource for research

The California Neurology Society is supporting a statewide prospective registry to advance understanding of Multiple Sclerosis (MS) and related autoimmune neurological diseases. Led by Principal Investigator Dr. Johanna Rosenthal, this collaborative effort brings together neurologists from Arrowhead Regional Medical Center, Riverside Community Hospital, and across California.

This registry collects de‑identified laboratory and clinical data—including immunoglobulin subclasses, lymphocyte populations, and flow cytometry results—to evaluate how modern Disease Modifying Therapies (DMTs) affect the immune system.

Participating neurologists submit data from consenting adult patients, with testing performed at standardized intervals before and after treatment.

By freezing and analyzing data quarterly, the registry aims to provide clinicians with meaningful insights into treatment response, support evidence‑based use of high‑cost therapies, and create a long‑term resource for research. The project includes an initial one‑year cohort of 100 patients, with potential for expansion based on findings.

If interested in joining the registry please contact Johanna Rosenthal, MD via text at 714-213-0492 or by email at johanna.rosenthal@cusm.edu.